Found 6 matching trials
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of IONIS APO(a)-LRx in Healthy Volunteers With Elevated Lipoprotein(a)
PHASE1The purpose is to assess the safety, tolerability, pharmacokinetics, and ph...
Drug-drug Interaction Study to Evaluate the Effect of ISIS 681257 on Clopidogrel
PHASE1This is a single center, open label, single sequence, two treatment, two-pe...
A Study to Assess Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Pelacarsen (ISIS 681257) in Healthy Japanese Participants
PHASE1The purpose of the study is to assess the safety, tolerability, and pharmac...
Location
Parexel International
Phase 2 Study of ISIS 681257 (AKCEA-APO(a)-LRx) in Participants With Hyperlipoproteinemia(a) and Cardiovascular Disease
PHASE2This is a multicenter, randomized, double-blind, placebo-controlled, dose-r...
Study of ISIS 681257 in Patients With Renal Impairment Compared to Healthy Patients
PHASE1This is a Phase 1, Multicenter, Open-Label, Parallel Group Adaptive Pharmac...
Drug-drug Interaction Study to Evaluate the Effect of ISIS 681257 on Warfarin
PHASE1This is a single center, open label, single sequence, two-treatment, two-pe...